RETA GLP-3

Description

RETA GLP-3 — Retatrutide, Triple GIP/GLP-1/Glucagon Receptor Agonist Peptide

RETA GLP-3 is a synthetic peptide analogue, known in the pharmacological literature as retatrutide, engineered as a single-chain agonist acting at the GIP, GLP-1 and glucagon receptors. It is produced by solid-phase synthesis and supplied for in vitro laboratory research use only.

Research context

Published preclinical literature has characterised retatrutide’s binding affinity and cAMP-accumulation activity at GIP, GLP-1 and glucagon receptors using transfected cell-line systems such as HEK293 and CHO-derived receptor-expression models. Comparative receptor-pharmacology studies have examined its signal-transduction kinetics and receptor-selectivity profile relative to single- and dual-receptor agonist peptides. Receptor-binding assays and functional cAMP-signalling assays remain the primary in vitro methodologies applied to this compound in the literature. Structure-function work has further examined how specific sequence substitutions relative to native incretin hormones correlate with the observed differences in binding kinetics across the three target receptors, using radioligand-displacement and reporter-gene assay formats.

Specification

• Available sizes: 5mg · 10mg · 15mg · 20mg · 30mg · 60mg
• Form: lyophilised powder
• Purity: ≥99% (HPLC)
• Testing: independently lot-tested by Horizon Analytical · Certificate of Analysis per lot

For laboratory research use only. This material is supplied to qualified researchers and institutions for in vitro investigational use. It is not a drug, food, cosmetic or medical device. It is not intended for human or veterinary use, for diagnosis, treatment, cure or prevention of any disease, or for any use outside a controlled laboratory environment. No statement on this site has been evaluated by the Food and Drug Administration. Keep out of reach of children.

Related Research

Compound family: Tirzepatide, Semaglutide, Dulaglutide, Liraglutide, Reta + Tirz (20mg + 40mg)

Browse: Metabolic Research · All Research Peptides

Reconstitution & Lab Testing: All products independently tested by Horizon Analytical. See our Reconstitution & Lab Testing FAQ. Reconstitution typically requires BAC Water.