Sema GLP-1

Description

Sema GLP-1 — Semaglutide, GLP-1 Receptor Agonist Peptide

Sema GLP-1 is a synthetic peptide analogue, known in the pharmacological literature as semaglutide, engineered as a long-acting agonist acting at the GLP-1 receptor. It is produced by solid-phase synthesis and supplied for in vitro laboratory research use only.

Research context

Published in vitro literature has examined semaglutide’s binding affinity and cAMP-accumulation activity at the GLP-1 receptor in transfected cell lines, including pancreatic beta-cell line model systems used to characterise receptor-mediated signal transduction. Structure-activity studies have examined the fatty-acid side-chain modification that extends its plasma protein-binding profile relative to earlier GLP-1 receptor agonist peptides. Receptor-binding and functional signalling assays, including radioligand-displacement and cAMP reporter-gene formats, remain the standard in vitro methodology applied to this compound. Comparative pharmacokinetic-modelling studies in cell-free systems have also examined its proteolytic-degradation resistance and extended plasma half-life relative to native GLP-1, using enzymatic-digestion and protein-binding assay formats.

Specification

• Available sizes: 5mg · 10mg · 15mg · 20mg · 50mg
• Form: lyophilised powder
• Purity: ≥99% (HPLC)
• Testing: independently lot-tested by Horizon Analytical · Certificate of Analysis per lot

For laboratory research use only. This material is supplied to qualified researchers and institutions for in vitro investigational use. It is not a drug, food, cosmetic or medical device. It is not intended for human or veterinary use, for diagnosis, treatment, cure or prevention of any disease, or for any use outside a controlled laboratory environment. No statement on this site has been evaluated by the Food and Drug Administration. Keep out of reach of children.

Related Research

Compound family: Retatrutide, Tirzepatide, Cagrisema (2.5mg + 2.5mg), Cagrisema (5mg + 5mg)

Browse: Metabolic Research · All Research Peptides

Reconstitution & Lab Testing: All products independently tested by Horizon Analytical. See our Reconstitution & Lab Testing FAQ. Reconstitution typically requires BAC Water.