HGH Fragment 176-191

Description

HGH Fragment 176-191 — Stabilised hGH C-Terminal Fragment Peptide

HGH Fragment 176-191, supplied for in vitro laboratory research use only, is a stabilised synthetic fragment corresponding to the C-terminal region, amino acids 176–191, of the human growth-hormone sequence, structurally isolated from the full-length hormone’s principal receptor-binding domain. It is produced by solid-phase synthesis.

Research context

Published biochemical literature has examined this fragment’s lack of binding to the growth-hormone receptor’s primary binding site, distinguishing its in vitro activity from that of full-length growth hormone in receptor-binding assay systems. Studies using isolated adipocyte cell-culture models have examined lipolytic enzyme activation and lipogenic enzyme expression following fragment exposure, independent of growth-hormone receptor-mediated signalling pathways. These structure-activity assay systems form the basis of the published literature on the fragment. Comparative in vitro work has also examined the fragment’s stability against proteolytic degradation relative to full-length growth hormone, using cell-free enzymatic-digestion assay formats.

Specification

• Available sizes: 1mg · 2mg · 5mg · 10mg · 12mg · 15mg
• Form: lyophilised powder
• Purity: ≥99% (HPLC)
• Testing: independently lot-tested by Horizon Analytical · Certificate of Analysis per lot

For laboratory research use only. This material is supplied to qualified researchers and institutions for in vitro investigational use. It is not a drug, food, cosmetic or medical device. It is not intended for human or veterinary use, for diagnosis, treatment, cure or prevention of any disease, or for any use outside a controlled laboratory environment. No statement on this site has been evaluated by the Food and Drug Administration. Keep out of reach of children.

Related Research

Compound family: HGH, IGF-1 LR3, AOD9604, Lipo-C

Browse: Metabolic Research · All Research Peptides

Reconstitution & Lab Testing: All products independently tested by Horizon Analytical. See our Reconstitution & Lab Testing FAQ. Reconstitution typically requires BAC Water.