Eloralintide

Description

Eloralintide: A Selective Amylin Receptor Agonist for Metabolic Pathway Research

Explore the frontier of selective receptor pharmacology. At Next Level Pharm, we supply forward-thinking researchers with the precision compounds required to interrogate complex signaling systems, and Eloralintide is a defining tool for advanced amylin pathway investigation.

Engineered as a lipidated 37-residue analog of human amylin, this compound allows your lab to map the amylin receptor family with a degree of selectivity that non-selective analogs cannot provide, distinguishing AMY1R activity from calcitonin receptor background in your in vitro models.

Why Anchor Your Studies with Eloralintide?

• True Receptor Selectivity: Observe amylin signaling without the confound. In published cAMP activation assays, Eloralintide is approximately 11-fold more potent at AMY1R than at AMY3R and 12-fold more potent than at the calcitonin receptor — a clean separation that dual-agonist compounds do not deliver.
• Engineered Stability: The native amylin disulfide bridge is replaced by a methylene thioacetal bond between Cys2 and Cys7, and three non-coded residues sit at positions 11, 15 and 22. The result is a molecule built for reproducible handling rather than one that fibrillates in your buffer.
• Extended Exposure Profile: Lys26 carries a gamma-Glu-gamma-Glu-C20 diacid side chain that drives albumin binding and an extended plasma half-life, supporting flat, low-variance exposure across long-run study designs.
• Lab-Ready Handling: Supplied lyophilized for effortless reconstitution, allowing your team to maintain a smooth, uninterrupted workflow while observing long-term signaling rhythms.

Expand your laboratory’s investigational horizons with Next Level Pharm.

IMPORTANT DISCLAIMER: > This product is strictly for research use only, and is not for human or veterinary use. It should also be kept out of reach of children. Eloralintide is an investigational compound and is not approved by the FDA for any use.

Related Research

Compound family: Cagrilintide, Cagrisema (2.5mg + 2.5mg), Cagrisema (5mg + 5mg), Cagrisema (10mg + 10mg)

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Reconstitution & Lab Testing: All products independently tested by Horizon Analytical. See our Reconstitution & Lab Testing FAQ. Reconstitution typically requires BAC Water.