LL-37

Description

LL-37 — Human Cathelicidin Antimicrobial Peptide

LL-37 is the only human cathelicidin-derived antimicrobial peptide (AMP) identified to date. It is supplied for in vitro laboratory research only.

Research context

Preclinical literature has examined LL-37 in cathelicidin antimicrobial peptide assays against bacterial, fungal and viral membrane preparations, including minimum-inhibitory-concentration (MIC) assay formats. Innate immune cell chemotaxis assays and lipopolysaccharide-binding studies have also used this peptide to characterise its role in pattern-recognition and leukocyte recruitment pathways in vitro. Structure-activity studies using truncated and substituted LL-37 analogues have further characterised the peptide domains responsible for membrane interaction within these assay systems.

Specification

• Available sizes: 5mg
• Form: lyophilised powder
• Purity: ≥99% (HPLC)
• Testing: independently lot-tested by Horizon Analytical · Certificate of Analysis per lot

For laboratory research use only. This material is supplied to qualified researchers and institutions for in vitro investigational use. It is not a drug, food, cosmetic or medical device. It is not intended for human or veterinary use, for diagnosis, treatment, cure or prevention of any disease, or for any use outside a controlled laboratory environment. No statement on this site has been evaluated by the Food and Drug Administration. Keep out of reach of children.

Related Research

Compound family: BPC-157, Dermorphin, B7-33, NAD+

Browse: Dermatological Research · All Research Peptides

Reconstitution & Lab Testing: All products independently tested by Horizon Analytical. See our Reconstitution & Lab Testing FAQ. Reconstitution typically requires BAC Water.