Description
Semax — ACTH(4-10) Heptapeptide Analogue
Semax is a synthetic heptapeptide analogue of the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10), supplied for in vitro laboratory research only.
Research context
Preclinical literature has examined Semax in cell-culture and animal models of BDNF and NGF expression, dopaminergic and serotonergic receptor signalling, and monoamine turnover. Investigators use it in receptor-binding assays, HPLC analysis of catecholamine and indoleamine metabolites, and rodent behavioural-pharmacology model systems designed to probe neurotrophic signalling pathways. Reported study designs also include enzyme-linked immunoassays quantifying BDNF and NGF protein expression in cortical and hippocampal tissue samples, alongside electrophysiological recordings examining synaptic transmission in ex vivo brain-slice preparations. As an ACTH-fragment analogue, Semax is also referenced in comparative pharmacology literature alongside related melanocortin-derived peptide fragments, with additional preclinical designs pairing chromatographic stability studies in biological matrices with gene-expression analyses of monoamine-synthesis enzymes in cultured neural tissue.
Specification
- Available sizes: 5mg · 10mg
- Form: lyophilised powder
- Purity: ≥99% (HPLC)
- Testing: independently lot-tested by Horizon Analytical · Certificate of Analysis per lot
For laboratory research use only. This material is supplied to qualified researchers and institutions for in vitro investigational use. It is not a drug, food, cosmetic or medical device. It is not intended for human or veterinary use, for diagnosis, treatment, cure or prevention of any disease, or for any use outside a controlled laboratory environment. No statement on this site has been evaluated by the Food and Drug Administration. Keep out of reach of children.
Related Research
Compound family: Selank, Cerebrolysin, Humanin, PE-22-28
Browse: Neuropeptide Research · All Research Peptides
Reconstitution & Lab Testing: All products independently tested by Horizon Analytical. See our Reconstitution & Lab Testing FAQ. Reconstitution typically requires BAC Water.










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