PTD-DBM

Description

PTD-DBM — Wnt/β-Catenin Pathway Modulator

PTD-DBM (Protein Transduction Domain-Dvl-Binding Motif) is a synthetic, cell-permeable peptide that interferes with the interaction between CXXC5 and Dishevelled (Dvl). It is supplied for in vitro laboratory research only.

Research context

Preclinical literature has examined this compound in cell and tissue culture models of Wnt/β-catenin pathway signalling, including assays of β-catenin accumulation and CXXC5-Dvl protein-protein interaction disruption. Follicular stem cell culture models have been used to study telogen-to-anagen transition signalling, and co-exposure studies with other growth-factor pathway modulators have examined combined Wnt-pathway responses in vitro. Mass-spectrometry-based methods have also been used to confirm peptide integrity and CXXC5-Dvl complex disruption across these in vitro assay conditions.

Specification

• Available sizes: 1mg
• Form: lyophilised powder
• Purity: ≥99% (HPLC)
• Testing: independently lot-tested by Horizon Analytical · Certificate of Analysis per lot

For laboratory research use only. This material is supplied to qualified researchers and institutions for in vitro investigational use. It is not a drug, food, cosmetic or medical device. It is not intended for human or veterinary use, for diagnosis, treatment, cure or prevention of any disease, or for any use outside a controlled laboratory environment. No statement on this site has been evaluated by the Food and Drug Administration. Keep out of reach of children.

Related Research

Compound family: Melanotan I, Melanotan II, AHK-Cu, GHK-Cu

Browse: Dermatological Research · All Research Peptides

Reconstitution & Lab Testing: All products independently tested by Horizon Analytical. See our Reconstitution & Lab Testing FAQ. Reconstitution typically requires BAC Water.