Humanin

Description

Humanin — Mitochondrial-Derived Peptide (MDP)

Humanin is a 24-amino-acid peptide encoded within the mitochondrial genome, supplied for in vitro laboratory research only.

Research context

Published preclinical work has examined Humanin in cell-culture models of Bax-mediated apoptosis signalling, the formyl peptide receptor-like 1 (FPRL1) and the WSX-1/CNTFR/gp130 tripartite receptor complex, and IGFBP-3 binding interactions. Investigators use it in assays of mitochondrial-derived peptide signalling and cellular stress-response pathways across multiple cell lines, including studies of glucose-handling and insulin-signalling pathways at the receptor level. Reported study designs include caspase-activity assays, mitochondrial membrane-potential measurements, and competitive binding assays characterising receptor affinity, together with gene-expression analyses examining downstream signal-transduction cascades in cultured neuronal and non-neuronal cell lines. As a member of the broader mitochondrial-derived peptide (MDP) family, Humanin is also referenced in comparative pharmacology literature alongside related MDP sequences, with additional preclinical designs pairing binding-affinity assays with chromatographic stability studies characterising the peptide’s behaviour in biological matrices.

Specification

• Available sizes: 10mg
• Form: lyophilised powder
• Purity: ≥99% (HPLC)
• Testing: independently lot-tested by Horizon Analytical · Certificate of Analysis per lot

For laboratory research use only. This material is supplied to qualified researchers and institutions for in vitro investigational use. It is not a drug, food, cosmetic or medical device. It is not intended for human or veterinary use, for diagnosis, treatment, cure or prevention of any disease, or for any use outside a controlled laboratory environment. No statement on this site has been evaluated by the Food and Drug Administration. Keep out of reach of children.

Related Research

Compound family: Cerebrolysin, Selank, Semax, Cardiogen

Browse: Neuropeptide Research · All Research Peptides

Reconstitution & Lab Testing: All products independently tested by Horizon Analytical. See our Reconstitution & Lab Testing FAQ. Reconstitution typically requires BAC Water.