Adamax

Description

Adamax — Acetylated, Adamantane-Modified SEMAX Analogue

Adamax is a structurally modified analogue of the ACTH(4-10) heptapeptide SEMAX, incorporating an adamantane substituent and N-terminal acetylation, supplied for in vitro laboratory research only.

Research context

Preclinical literature on this analogue class has examined activity in cell-culture and animal models of BDNF and TrkB receptor signalling, synaptic protein expression, and monoamine turnover. Investigators use it in receptor-binding assays comparing signalling duration and proteolytic stability against the parent SEMAX sequence, frequently using HPLC-based stability assays and enzymatic degradation studies in plasma and tissue homogenates. Reported model systems also include rodent behavioural-pharmacology designs and ex vivo electrophysiological recordings examining synaptic transmission and receptor-level signal transduction following structural modification of the parent peptide. As a structurally stabilised SEMAX analogue, Adamax is also referenced in comparative pharmacology literature examining structure-activity relationships across ACTH-fragment derivatives, with additional study designs characterising its degradation profile relative to the unmodified heptapeptide sequence.

Specification

• Available sizes: 5mg · 10mg
• Form: lyophilised powder
• Purity: ≥99% (HPLC)
• Testing: independently lot-tested by Horizon Analytical · Certificate of Analysis per lot

For laboratory research use only. This material is supplied to qualified researchers and institutions for in vitro investigational use. It is not a drug, food, cosmetic or medical device. It is not intended for human or veterinary use, for diagnosis, treatment, cure or prevention of any disease, or for any use outside a controlled laboratory environment. No statement on this site has been evaluated by the Food and Drug Administration. Keep out of reach of children.

Related Research

Compound family: Cerebrolysin, Semax, Selank, Cortagen

Browse: Neuropeptide Research · All Research Peptides

Reconstitution & Lab Testing: All products independently tested by Horizon Analytical. See our Reconstitution & Lab Testing FAQ. Reconstitution typically requires BAC Water.